DISEASES OF OTHER ENDOCRINE GLANDS (250-259)
Diabetes mellitus
Other disorders of pancreatic internal secretion
Disorders of parathyroid gland
Disorders of the pituitary gland and its hypothalamic control
Diseases of thymus gland
Disorders of adrenal glands
Ovarian dysfunction
Testicular dysfunction
Polyglandular dysfunction and related disorders
Other endocrine disorders
250 Diabetes mellitus
Excludes: gestational diabetes (648.8)
hyperglycemia NOS (790.6)
neonatal diabetes mellitus (775.1)
nonclinical diabetes (790.2)
The following fifth-digit subclassification is for use with category 250:
0 type II [non-insulin dependent type] [NIDDM type] [adult-onset type] or unspecified type, not stated as uncontrolled
Fifth-digit 0 is for use for type II, adult-onset, diabetic patients, even if the patient requires insulin
1 type I [insulin dependent type] [IDDM] [juvenile type], not stated as uncontrolled
2 type II [non-insulin dependent type] [NIDDM type] [adult-onset type] or unspecified type, uncontrolled
Fifth-digit II is for use for type II, adult-onset, diabetic patients, even if the patient requires insulin
3 type I [insulin dependent type] [IDDM] [juvenile type], uncontrolled
250.0 Diabetes mellitus without mention of complication
Diabetes mellitus without mention of complication or manifestation classifiable to 250.1-250.9
Diabetes (mellitus) NOS
250.1 Diabetes with ketoacidosis
Diabetic:
acidosis without mention of coma
ketosis without mention of coma
250.2 Diabetes with hyperosmolarity
Hyperosmolar (nonketotic) coma
250.3 Diabetes with other coma
Diabetic coma (with ketoacidosis)
Diabetic hypoglycemic coma
Insulin coma NOS
Excludes: diabetes with hyperosmolar coma (250.2)
250.4 Diabetes with renal manifestations
Use additional code to identify manifestation, as:
diabetic:
nephropathy NOS (583.81)
nephrosis (581.81)
intercapillary glomerulosclerosis (581.81)
Kimmelstiel-Wilson syndrome (581.81)
250.5 Diabetes with ophthalmic manifestations
Use additional code to identify manifestation, as:
diabetic:
blindness (369.00-369.9)
cataract (366.41)
glaucoma (365.44)
retinal edema (362.83)
retinopathy (362.01-362.02)
250.6 Diabetes with neurological manifestations
Use additional code to identify manifestation, as:
diabetic:
amyotrophy (358.1)
mononeuropathy (354.0-355.9)
neurogenic arthropathy (713.5)
peripheral autonomic neuropathy (337.1)
polyneuropathy (357.2)
250.7 Diabetes with peripheral circulatory disorders
Use additional code to identify manifestation, as:
diabetic:
gangrene (785.4)
peripheral angiopathy (443.81)
250.8 Diabetes with other specified manifestations
Diabetic hypoglycemia
Hypoglycemic shock
Use additional code to identify manifestation, as:
any associated ulceration (707.10-707.9)
diabetic bone changes (731.8)
Use additional E code to identify cause, if drug-induced
250.9 Diabetes with unspecified complication
251 Other disorders of pancreatic internal secretion
251.0 Hypoglycemic coma
Iatrogenic hyperinsulinism
Non-diabetic insulin coma
Use additional E code to identify cause, if drug-induced
Excludes: hypoglycemic coma in diabetes mellitus (250.3)
251.1 Other specified hypoglycemia
Hyperinsulinism:
NOS
ectopic
functional
Hyperplasia of pancreatic islet beta cells NOS
Excludes: hypoglycemia in diabetes mellitus (250.8)
hypoglycemia in infant of diabetic mother (775.0)
hypoglycemic coma (251.0)
neonatal hypoglycemia (775.6)
Use additional E code to identify cause, if drug-induced
251.2 Hypoglycemia, unspecified
Hypoglycemia:
NOS
reactive
spontaneous
Excludes: hypoglycemia:
with coma (251.0)
in diabetes mellitus (250.8)
leucine-induced (270.3)
251.3 Postsurgical hypoinsulinemia
Hypoinsulinemia following complete or partial pancreatectomy
Postpancreatectomy hyperglycemia
251.4 Abnormality of secretion of glucagon
Hyperplasia of pancreatic islet alpha cells with glucagon excess
251.5 Abnormality of secretion of gastrin
Hyperplasia of pancreatic alpha cells with gastrin excess
Zollinger-Ellison syndrome
251.8 Other specified disorders of pancreatic internal secretion
251.9 Unspecified disorder of pancreatic internal secretion
Islet cell hyperplasia NOS
252 Disorders of parathyroid gland
252.0 Hyperparathyroidism
Hyperplasia of parathyroid
Osteitis fibrosa cystica generalisata
von Recklinghausen's disease of bone
Excludes: ectopic hyperparathyroidism (259.3)
secondary hyperparathyroidism (of renal origin) (588.8)
252.1 Hypoparathyroidism
Parathyroiditis (autoimmune)
Tetany:
parathyroid
parathyroprival
Excludes: pseudohypoparathyroidism (275.49)
pseudopseudohypoparathyroidism (275.49)
tetany NOS (781.7)
transitory neonatal hypoparathyroidism (775.4)
252.8 Other specified disorders of parathyroid gland
Cyst of parathyroid gland
Hemorrhage of parathyroid gland
252.9 Unspecified disorder of parathyroid gland
253 Disorders of the pituitary gland and its hypothalamic control
Includes: the listed conditions whether the disorder is in the pituitary or the hypothalamus
Excludes: Cushing's syndrome (255.0)
253.0 Acromegaly and gigantism
Overproduction of growth hormone
253.1 Other and unspecified anterior pituitary hyperfunction
Forbes-Albright syndrome
Excludes: overproduction of:
ACTH (255.3)
thyroid-stimulating hormone [TSH] (242.8)
253.2 Panhypopituitarism
Cachexia, pituitary
Necrosis of pituitary (postpartum)
Pituitary insufficiency NOS
Sheehan's syndrome
Simmonds' disease
Excludes: iatrogenic hypopituitarism (253.7)
253.3 Pituitary dwarfism
Isolated deficiency of (human) growth hormone [HGH]
Lorain-Levi dwarfism
253.4 Other anterior pituitary disorders
Isolated or partial deficiency of an anterior pituitary hormone, other than growth hormone
Prolactin deficiency
253.5 Diabetes insipidus
Vasopressin deficiency
Excludes: nephrogenic diabetes insipidus (588.1)
253.6 Other disorders of neurohypophysis
Syndrome of inappropriate secretion of antidiuretic hormone [ADH]
Excludes: ectopic antidiuretic hormone secretion (259.3)
253.7 Iatrogenic pituitary disorders
Hypopituitarism:
hormone-induced
hypophysectomy-induced
postablative
radiotherapy-induced
Use additional E code to identify cause
253.8 Other disorders of the pituitary and other syndromes of diencephalohypophyseal origin
Abscess of pituitary
Adiposogenital dystrophy
Cyst of Rathke's pouch
Fröhlich's syndrome
Excludes: craniopharyngioma (237.0)
253.9 Unspecified
Dyspituitarism
254 Diseases of thymus gland
Excludes: aplasia or dysplasia with immunodeficiency (279.2)
hypoplasia with immunodeficiency (279.2)
myasthenia gravis (358.0)
254.0 Persistent hyperplasia of thymus
Hypertrophy of thymus
254.1 Abscess of thymus
254.8 Other specified diseases of thymus gland
Atrophy of thymus
Cyst of thymus
Excludes: thymoma (212.6)
254.9 Unspecified disease of thymus gland
255 Disorders of adrenal glands
Includes: the listed conditions whether the basic disorder is in the adrenals or is pituitary-induced
255.0 Cushing's syndrome
Adrenal hyperplasia due to excess ACTH
Cushing's syndrome:
NOS
iatrogenic
idiopathic
pituitary-dependent
Ectopic ACTH syndrome
Iatrogenic syndrome of excess cortisol
Overproduction of cortisol
Use additional E code to identify cause, if drug-induced
Excludes: congenital adrenal hyperplasia (255.2)
255.1 Hyperaldosteronism
Aldosteronism (primary) (secondary)
Bartter's syndrome
Conn's syndrome
255.2 Adrenogenital disorders
Adrenogenital syndromes, virilizing or feminizing, whether acquired or associated with congenital adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
Achard-Thiers syndrome
Congenital adrenal hyperplasia
Female adrenal pseudohermaphroditism
Male:
macrogenitosomia praecox
sexual precocity with adrenal hyperplasia
Virilization (female) (suprarenal)
Excludes: adrenal hyperplasia due to excess ACTH (255.0)
isosexual virilization (256.4)
255.3 Other corticoadrenal overactivity
Acquired benign adrenal androgenic overactivity
Overproduction of ACTH
255.4 Corticoadrenal insufficiency
Addisonian crisis
Addison's disease NOS
Adrenal:
atrophy (autoimmune)
calcification
crisis
hemorrhage
infarction
insufficiency NOS
Excludes: tuberculous Addison's disease (017.6)
255.5 Other adrenal hypofunction
Adrenal medullary insufficiency
Excludes: Waterhouse-Friderichsen syndrome (meningococcal) (036.3)
255.6 Medulloadrenal hyperfunction
Catecholamine secretion by pheochromocytoma
255.8 Other specified disorders of adrenal glands
Abnormality of cortisol-binding globulin
255.9 Unspecified disorder of adrenal glands
256 Ovarian dysfunction
256.0 Hyperestrogenism
256.1 Other ovarian hyperfunction
Hypersecretion of ovarian androgens
256.2 Postablative ovarian failure
Ovarian failure:
iatrogenic
postirradiation
postsurgical
Use additional code for states associated with artificial menopause (627.4)
Excludes: acquired absence of ovary (V45.77)
asymptomatic age-related (natural) postmenopausal status (V49.81)
256.3 Other ovarian failure
Use additional code for states associated with natural menopause (627.2)
Excludes: asymptomatic age-related (natural) postmenopausal status (V49.81)
256.31 Premature menopause
256.39 Other ovarian failure
Delayed menarche
Ovarian hypofunction
Primary ovarian failure NOS
256.4 Polycystic ovaries
Isosexual virilization Stein-Leventhal syndrome
256.8 Other ovarian dysfunction
256.9 Unspecified ovarian dysfunction
257 Testicular dysfunction
257.0 Testicular hyperfunction
Hypersecretion of testicular hormones
257.1 Postablative testicular hypofunction
Testicular hypofunction:
iatrogenic
postirradiation
postsurgical
257.2 Other testicular hypofunction
Defective biosynthesis of testicular androgen
Eunuchoidism:
NOS
hypogonadotropic
Failure:
Leydig's cell, adult
seminiferous tubule, adult
Testicular hypogonadism
Excludes: azoospermia (606.0)
257.8 Other testicular dysfunction
Goldberg-Maxwell syndrome
Male pseudohermaphroditism with testicular feminization
Testicular feminization
257.9 Unspecified testicular dysfunction
258 Polyglandular dysfunction and related disorders
258.0 Polyglandular activity in multiple endocrine adenomatosis
Wermer's syndrome
258.1 Other combinations of endocrine dysfunction
Lloyd's syndrome
Schmidt's syndrome
258.8 Other specified polyglandular dysfunction
258.9 Polyglandular dysfunction, unspecified
259 Other endocrine disorders
259.0 Delay in sexual development and puberty, not elsewhere classified
Delayed puberty
259.1 Precocious sexual development and puberty, not elsewhere classified
Sexual precocity:
NOS
constitutional
cryptogenic
idiopathic
259.2 Carcinoid syndrome
Hormone secretion by carcinoid tumors
259.3 Ectopic hormone secretion, not elsewhere classified
Ectopic:
antidiuretic hormone secretion [ADH]
hyperparathyroidism
Excludes: ectopic ACTH syndrome (255.0)
259.4 Dwarfism, not elsewhere classified
Dwarfism:
NOS
constitutional
Excludes: dwarfism:
achondroplastic (756.4)
intrauterine (759.7)
nutritional (263.2)
pituitary (253.3)
renal (588.0)
progeria (259.8)
259.8 Other specified endocrine disorders
Pineal gland dysfunction
Progeria
Werner's syndrome
259.9 Unspecified endocrine disorder
Disturbance:
endocrine NOS
hormone NOS
Infantilism NOS